Experience with Autologous Pericardial Patch Closure of Ventricular Septal Defect
Iraqi Postgraduate Medical Journal,
2016, Volume 15, Issue 1, Pages 58-60
Conventionally,VentricularSeptal Defects(VSDs) are repaired with synthetic patch-Dacron(polyetheylene terephthalate) or Goretex(expanded polytetraflouroethylene).Recently,we began using glutaraldehyde-treated autologous pericardial patch to repair VSDs.We review our experience.
In this study,we are evaluating the result of closure of VSD by pericardial patch instead of synthetic patch.
MATERIALS AND METHOD:
BetweenGanuary 2009 to April 2014,60 children had their VSDs repairewith glutaraldehyde-treated autologous percardium.There were 20 males and 40 females, aged between 2 years and 12 years with amedian age of 4 years.The diagnosis was isolated VSD in 49 patients,multiple VSD in 3:Tetralogy of Fallot(TOF) in 8 patients The chest was opened by median sternotomyincision.After establishing cardiopulmonary bypass,a strip of pericardium was harvasted from patient and fixed in 0.6% glutaraldehyde for about 25 minutes.It was then washed out with 0.9% saline solution.The defect was repaired with 4/0 suture using a continous suture technique.
There was no hospital mortality. Postoperative echocardiogram reveald trivial leaking in 10 patients.Follow up was for 3 to 6 months(mean 2 months). No patient required reoperation for residual VSD.
Glutaraldehyd-treated autologous pericardium is an exellent material for surgical patch closure of VSD.It is easily available and does not require sterilization.
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