Iraqi Postgraduate Medical Journal

Abstract

ABSTRACT:
BACKGROUND:
Iron deficiency could have an adverse effect on the health of pregnant women and their fetuses. In present, no marker could be considered as the ideal for the detection of Iron deficiency anemia in pregnant women. Some authors suggested that soluble transferrin receptor-ferritin index could be a promising marker for iron deficiency during third trimester of pregnancy.
OBJECTIVE:
To study the value of soluble transferrin receptor - ferritin index as a marker for iron deficiency during third trimester.
PATIENTS AND METHOD:
A cross-sectional study conducted at the Antenatal clinic in Al Zahra’a maternity and children hospital and Baquba Teaching Hospital in Diyala province /Iraq, during the period from 17th march 2016 to the end of March 2017, seventy pregnant women were included in the study. Hemoglobin, CBC, HCT, MCV, and RDW-CV were tested by using automated device. Serum Ferritin and Transferrin receptor was tested by using ELISA kit,
RESULT:
The mean age of the women was 28.3 ± 6.5 (range: 16 – 48) years . Iron deficiency anemia was reported in 32% of the studied group. Serum Iron and Ferritin were significantly lower in iron deficiency anemia group than normal group, (P<0.05). Soluble Transferrin receptor (sTfR) and sTfR- ferritin index were significantly higher in iron deficiency anemia group than the normal group (P<0.05).
CONCLUSION:
S. ferritin is excellent predictor of IDA and had higher sensitivity, specificity and accuracy rates than sTfR and sTfR-F index. Additionally, the validity parameters of sTfR-F index were higher than that of sTfR.
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