Iraqi Postgraduate Medical Journal

Abstract

ABSTRACT:
BACKGROUND:
The 21st century has been set to enhance dialysis adequacy. Numerous studies have confirmed the association between the delivered dose of hemodialysis and patients outcomes. There is thus some evidence regarding the relationship between dialysis dose and quality of life.
OBJECTIVE:
To assess dialysis adequacy using (Urea Reduction Rate and KT/V), and to determine the association between dialysis dose and different Hemodialysis characteristics in children with End Stage Renal Failure undergoing Hemodialysis.
METHOD:
This was an observational cross-sectional study that was conducted for three months, from (November 2014 till January 2015); we enrolled 50 children with End Stage Renal Failure in four hemodialysis centers in Baghdad. Samples for blood urea (predialysis and postdialysis) were drown to calculate the adequacy dose.
RESULTS:
Thirty two (64%) of patients were male and 18(36%) were females; with male to female ratio was (1.7:1).The mean urea reduction ratio and Kt/V were 59.63 ± 7.345% and 1.29 ± 0.275, respectively, with fair dialysis adequacy .A Kt/V less than 1.2 and a urea reduction ratio less than 65% were found in 42%, and 38% of the hemodialysis patients, respectively. There was a significant correlation between dialysis dose and (Blood flow rate, Dialysis hours, Dialysis frequency /week and Effective surface area), while there was insignificance correlation with (gender, age, volume of ultrafiltration.
CONCLUSION:
Our results were better than neighbor countries with fair dialysis adequacy. It is important to regularly measure the parameters of dialysis adequacy in order to assess whether targets are achieved in accordance with K/DOQI guidelines.