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Risk Factors and Clinicopathological Characteristics among Patients with Gastric Cancer in Oncology Teaching Hospital

Iraqi Postgraduate Medical Journal, 2022, Volume 21, Issue 2, Pages 190-195
10.52573/ipmj.2021.174630

Abstract

BACKGROUND:
Gastric cancer is a rare tumor and one of the leading causes of death worldwide, unfortunately most of patient present late. 
PATIENTS AND METHODS:
Case -control study conducted on patients affected with gastric cancer presented to oncology teaching hospital. Data regarding their family history of gastric cancer, smoking and blood group were collected for patients and for participants in Control group matching in respect to age, sex, number and geographical area.          
OBJECTIVE:
Assess the most important risk factors of gastric cancer  Assess clinicpathologic and their histological subtypes
RESULT:
77 patients with stomach cancer and 77 control participants their age range from 27 up to 74. Mean age (SD) of (54 ± 13.8 and 55.1 ±13 years) respectively. A significant association between smoking and gastric cancer (62.3%) of index group compared to (39%) in control   (p=0.002). also a significant association between First degree family history of stomach cancer was found in 11.7% in index group compared to (0%) in control (p= 0.001). The most frequent site for cancer was antrum 31.1% of cases. diffuse subtype of adenocarcinoma(50.6%). Stage IV formed the majority of patients (62.4%).
CONCLUSION:
Smoking and family history of first degree relative have strong association with gastric cancer. Majority of patients present at advanced stage 4 and diffuse type of adenocarcinoma. Antrum is the most affected part of the stomach.
 
Keywords:

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