Iraqi Postgraduate Medical Journal

Abstract

ABSTRACT:
BACKGROUND:
The aim of this study is to differentiate between virulence of two isolates ,one was isolated from
severe clinical symptoms of amebiasis isolate (A) the other was from asymptomatic carriers isolate
(B).
METHODS :
12 male hamsters were employed in this study , they were divided into 3 groups . 1st group (5
hamsters), inoculated intracecally with isolate isolate (A) from human case of severe amebiasis . 2nd
group (5 hamsters) inculated with isolate (B) from asymptomatic carriers .3rd group (2
hamsters)inoculated with saline solution as control group .
RESULTS :
1st group of hamsters showed a flask shaped ulcer with sever inflammation of cecum with liver
abscesses , after four weeks of infection The 2nd group showed only mild inflammation of cecum
without ulceration and liver abscess. While 3rd group were normal control group.
CONCLUTION:
Our study may be Considered as a step for Characterization of Entamoeba histolytica that cause the
invasive intestinal and extraintestinal amebiasis and E.dispar an intestinal commensal parasit in Iraq.