Histopathological Interpretation of Abnormal Uterine Bleeding After the Age of 40 Year
Iraqi Postgraduate Medical Journal,
2010, Volume 9, Issue 3, Pages 274-282
To delineat the frequancy and pattern of uterine lesions which result in abnormal uterine bleeding (AUB)after the age of 40 years.
To delineat the frequancy and pattern of uterine lesions which result in abnormal uterine bleeding (AUB after the age of 40 years) and to compare the result with other similar studies
Histopathological examination of the tissues obtained by curettage and/or hysterectomy play an important role in the diagnosis of the lesions which cause AUB..
Organic intrauterine lesions was found in 69 (19%) of the cases. These included chronic endometritis (7.7%), endometrial polyp (6%), malignancy (3.9%) and submucous leiomyoma (1.4%) .On the other hand, the commonest histopathological finding in patient with AUB due to dysfunctional cause was endometrial hyperplasia which was found in (30.3%) of the cases, (27%) were simple endometrial type (cystic glandular hyperplasia).
Postmenopausal bleeding is found in 76 cases (21%). Atrophic endometrium was the commonest finding of postmenopausal bleeding, which represented (34.2%). Endometrial adenocarcinoma was found in 3.3%.
Eighty-two cases underwent hysterectomy after initial curetting due to persistent uterine bleeding, the endometrial lesions of (79) patients were confirmed at hysterectomy making the diagnostic accuracy of D and C(96.3%). Other uterine lesions were found at hysterectomy such as adenomyosis and leiomyoma.
Dysfunctional uterine bleeding was the predominant cause of AUB in women above ( 40 ) years of age.
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