Determination of Endometrial Thickness Threshold for Prompt Biopsy in Postmenopausal Women Without Vaginal Bleeding
Iraqi Postgraduate Medical Journal,
2012, Volume 11, Issue 3, Pages 292-296
Transvaginal sonography is performed as part of a pelvic sonogram in postmenopausal women and images of the endometrium are frequently obtained . In asymptomatic postmenopausal women without vaginal bleeding, the threshold separating normal from abnormally thickened endometrium is not known.
To determine an endometrial thickness threshold using transvaginal sonography for prediction of endometrial cancer in postmenopausal women without vaginal bleeding (asymptomatic) .
The study group includes 100 asymptomatic postmenopausal women without vaginal bleeding, We measure the sensitivity and specificity of trasvaginal sonography in the prediction of cancer in asymptomatic postmenopausal women without vaginal bleeding at endometrial thickness ≤5mm ,5-10 mm &>10mm ,
Four cases (4) of cancer were detected at >10mm endometrial thickness. In asymptomatic postmenopausal women without vaginal bleeding the sensitivity 100% ,specificity 47.91% ,positive predictive values 7.40% and negative predictive values 100% at 10mm endomtrial thickness while at 5mm endomtrial thickness,the sensitivity 100% ,specificity 9.3% ,positive predictive values 4% and negative predictive values 100%
In asymptomatic postmenopausal women promotion for endometrial sampling if endometrial thickness >10mm seen by trasvaginal sonography give better positive predictive value, sensitivity & specificity than>5mm endometrial thicknes
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